Mina J. Bissell Ph.D. & Vectorspace AI Advance New Space Biosciences Division

  • DNA bases/genes
  • Carbohydrates
  • Proteins
  • Lipids
  • Mitochondria
  • Blood cells
  • Membrane receptors
  • Cell adhesion molecules
  • ECM
  • Immune cells
  • Stem cells
  • Endothelium
  • Exosomes
  • Clustered DNA damage
  • Persistent mutations and chromosome aberrations
  • Reduced DNA and cellular repair
  • Drastic G M block and altered cell cycle kinetics
  • Enhanced cytokine activation
  • Tumorigenesis at high dose, high-LET or HZE
  • Apoptosis, autophagy, senescence, mitotic catastrophe, necrosis
  • Altered gene expression and differentiation
  • Changes in cell-cell comms and non-targeted effects
  • Changes in cell adhesion and motility
  • Changes in angiogenesis

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